Get him or her to optimize your medication regimen when you have multiple diseases, one of them is a seizure disorder, and you absolutely need to take phenytoin.
This just in: Phenytoin sucks.
I don't mean in the sense that it is a bad drug. It is quite effective. It's just really, really, really, really annoying.
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It's that rare case of zero-order metabolism that makes it such a dosing nightmare. But then again, be glad you're not the patient, right?
And zero-order kinetics are just the beginning. That hepatic enzyme induction results in it not just inducing its own metabolism, but increasing the metabolism of a whole lot of other drugs.
But yes, you're quite right. I'd much rather dose phenytoin than be the patient. Seizure disorders are generally no fun.
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